Hypoxia upregulates neutrophil degranulation and potential for tissue injury
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چکیده
منابع مشابه
Hypoxia upregulates neutrophil degranulation and potential for tissue injury
BACKGROUND The inflamed bronchial mucosal surface is a profoundly hypoxic environment. Neutrophilic airway inflammation and neutrophil-derived proteases have been linked to disease progression in conditions such as COPD and cystic fibrosis, but the effects of hypoxia on potentially harmful neutrophil functional responses such as degranulation are unknown. METHODS AND RESULTS Following exposur...
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ژورنال
عنوان ژورنال: Thorax
سال: 2016
ISSN: 0040-6376,1468-3296
DOI: 10.1136/thoraxjnl-2015-207604